Our innovative cell-based assays serve as indispensable tools for biological and pharmaceutical research. From apoptosis and proliferation to metabolism and signal transduction, these assays streamline data collection and enhance experimental accuracy. We offer two types of cell-based assays: genetically modified assays and chemical-based assays. Genetically modified assays utilize custom-engineered cells that generate measurable outputs for enhanced data precision. Chemical-based assays leverage high-sensitivity dyes, antibodies, or proteins to monitor cellular changes and pathway dynamics.
Leveraging our team’s 20+ years of expertise, our metabolism assays are designed for use with live cells, lysates, and biofluids. They integrate seamlessly into workflows, offering rapid, plate-reader-compatible readouts that facilitate metabolic analysis across various disease areas.
Our cell viability assays, essential for researchers studying drug discovery, toxicology, and disease modeling, provide critical insights into cellular health, ensuring robust and reproducible results. Whether screening drug candidates or evaluating cellular responses, these solutions deliver actionable data. Our comprehensive assay portfolio includes metabolic assays, cytotoxicity assays, live/dead cell assays, and proliferation and cell cycle assays.
Metabolic assays such as MTT, MTS, XTT, WST-1, and resazurin evaluate energy production and mitochondrial function. ATP luminescence assays detect ATP as a viability marker, ideal for high-throughput applications. Cytotoxicity assays measure membrane integrity using LDH release and dye exclusion methods such as DRAQ7® and propidium iodide. Enzyme leakage assays, including LDH and adenylate kinase (AK) assays, provide reliable viability assessments.
Live/dead cell assays employ membrane-impermeable dyes and amine-reactive dyes to distinguish viable cells. Fluorescent-based assays ensure precise viability analysis, with careful controls required to minimize background fluorescence. Proliferation assays track cell division using EdU, BrdU, CFSE, and Ki67 markers. Clonogenic assays assess long-term survival, while senescence assays detect SA-beta-gal accumulation in aging cells.
Selecting the right assay depends on sensitivity, throughput, and experimental compatibility. Advanced techniques such as mitochondrial potential dyes, esterase cleavage assays, and glycolysis assays further enhance assay performance. Empower your research with our state-of-the-art cell-based bioassays, designed to deliver accuracy, efficiency, and meaningful biological insights.